Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 3/20 | 0.46 |
| ▸ | IAPP | P10997 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15711971 | 1.00 | LCK (0.49) | LCKAPPIAPPTRPV1ESR1 | |
| SCHEMBL8008620 | 0.83 | LCK (0.67) | LCKESR1ALOX15ALOX12MEN1 | |
| SCHEMBL19364381 | 0.82 | ITGB1 (0.53) | KDM4EALDH1A1MAPK1HIF1ALMNA | |
| SCHEMBL8007016 | 0.82 | LCK (0.48) | LCK | |
| SCHEMBL10099814 | 0.82 | ITGB3 (0.54) | LCKTRPV1MEN1KMT2AHSD17B10 | |
| SCHEMBL10099944 | 0.82 | LCK (0.48) | LCK | |
| SCHEMBL15711973 | 0.82 | ALOX15 (0.46) | TRPV1ESR1ALOX15ALDH1A1CYP3A4 | |
| SCHEMBL15711975 | 0.81 | ALOX15 (0.45) | TRPV1ALOX15ALDH1A1CYP3A4HPGD | |
| SCHEMBL8257343 | 0.81 | ALOX15 (0.57) | LCKAPPIAPPTRPV1ESR1 | |
| SCHEMBL1068518 | 0.81 | ALOX15 (0.57) | LCKAPPIAPPTRPV1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009101616-A9 | NOVEL CONJUGATES FOR TREATING NEURODEGENERATIVE DISEASES AND DISORDERS | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2010-06-24 | — | — | WO | disclosed |
| WO-2009101616-A1 | NOVEL CONJUGATES FOR TREATING NEURODEGENERATIVE DISEASES AND DISORDERS | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2009-08-20 | — | — | WO | disclosed |