Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.63 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | CASR | P41180 | 1/20 | 0.56 |
| ▸ | PYGL | P06737 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8007467 | 0.85 | MEN1 (0.62) | TAS1R3TAS1R1NPC1RAB9ACASR | |
| SCHEMBL8005414 | 0.81 | TAS1R3 (0.53) | TAS1R3TAS1R1NPC1RAB9ACASR | |
| Hydrochloric Acid SCHEMBL8005463 | 0.80 | TAS1R3 (0.52) | TAS1R3TAS1R1NPC1RAB9ACASR | |
| SCHEMBL11336178 | 0.77 | RAB9A (1.00) | TAS1R3TAS1R1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL700757 | 0.77 | TAS1R3 (1.00) | TAS1R3TAS1R1NPC1RAB9APYGL | |
| SCHEMBL2751208 | 0.76 | RAB9A (0.97) | TAS1R3TAS1R1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7995243 | 0.75 | NPC1 (0.57) | TAS1R3TAS1R1NPC1RAB9ACASR | |
| SCHEMBL444179 | 0.75 | CASR (0.74) | TAS1R3TAS1R1NPC1RAB9ACASR | |
| SCHEMBL7936481 | 0.73 | CCR3 (0.77) | — | |
| SCHEMBL25464439 | 0.73 | NPC1 (0.62) | TAS1R3TAS1R1NPC1RAB9ACASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060484-A | Anti-viral method | ELI LILLY AND COMPANY (US) | 2000-05-09 | — | — | US | disclosed |
| EP-0806205-A2 | Urea, thiourea and guanidine compounds and their use as anti-viral agents | ELI LILLY AND COMPANY (US) | 1997-11-12 | — | — | EP | disclosed |