Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | CASR | P41180 | 1/20 | 0.58 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.58 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PYGL | P06737 | 1/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.48 |
| ▸ | IL1B | P01584 | 1/20 | 0.48 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8004908 | 0.85 | TAS1R3 (0.63) | MEN1KMT2ACASRTAS1R3TAS1R1 | |
| SCHEMBL8005414 | 0.83 | TAS1R3 (0.53) | MEN1KMT2ACASRTAS1R3TAS1R1 | |
| Hydrochloric Acid SCHEMBL8005463 | 0.82 | TAS1R3 (0.52) | MEN1KMT2ACASRTAS1R3TAS1R1 | |
| SCHEMBL444179 | 0.79 | CASR (0.74) | MEN1KMT2ACASRTAS1R3TAS1R1 | |
| SCHEMBL3904395 | 0.77 | MEN1 (0.66) | MEN1KMT2ANPC1RAB9AP2RX7 | |
| SCHEMBL7936481 | 0.76 | CCR3 (0.77) | CCR3 | |
| SCHEMBL3902121 | 0.75 | MEN1 (0.64) | MEN1KMT2ANPC1RAB9AP2RX7 | |
| SCHEMBL2433439 | 0.74 | CASR (1.00) | CASRKCNQ2SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL8067991 | 0.74 | RAB9A (0.72) | MEN1KMT2ACASRTAS1R3TAS1R1 | |
| SCHEMBL8067993 | 0.74 | RAB9A (0.72) | MEN1KMT2ACASRTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060484-A | Anti-viral method | ELI LILLY AND COMPANY (US) | 2000-05-09 | — | — | US | disclosed |
| EP-0806205-A2 | Urea, thiourea and guanidine compounds and their use as anti-viral agents | ELI LILLY AND COMPANY (US) | 1997-11-12 | — | — | EP | disclosed |