SCHEMBL8005048

SCHEMBL8005048

CCCCCCCC/C=C\CCCCCCCCOCC(COCCCCCCCC/C=C\CCCCCCCC)NC(=O)SCCN(C)C

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PLA2G2C Q5R387 7/20 0.45
LPAR1 Q92633 2/20 0.40
LPAR3 Q9UBY5 2/20 0.40
P2RY10 O00398 2/20 0.39
CNR1 P21554 1/20 0.39
PLA2G4A P47712 1/20 0.39
EPHX2 P34913 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8013026 0.90 PLA2G2C (0.44) PLA2G2CLPAR1LPAR3P2RY10PLA2G4A
SCHEMBL8016657 0.88 PLA2G2C (0.42) PLA2G2CLPAR1LPAR3P2RY10CNR1
SCHEMBL8013905 0.84 DGKA (0.51) LPAR1LPAR3
SCHEMBL8021284 0.83 TLR2 (0.49) LPAR1LPAR3CNR1EPHX2
SCHEMBL18335360 0.82 FAAH (0.44) CNR1
SCHEMBL18335359 0.82 FAAH (0.44) CNR1
SCHEMBL8004013 0.81 PLA2G2C (0.46) PLA2G2CLPAR1LPAR3EPHX2
SCHEMBL8156016 0.81 PLA2G2C (0.46) PLA2G2CLPAR1LPAR3EPHX2
SCHEMBL8013286 0.81 PLA2G2C (0.46) PLA2G2CLPAR1LPAR3EPHX2
SCHEMBL8146592 0.81 PLA2G2C (0.46) PLA2G2CLPAR1LPAR3EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0685234-B1 DRUG COMPOSITION CONTAINING NUCLEIC ACID COPOLYMER NIPPON SHINYAKU CO LTD (JP) 2000-05-10 EP disclosed
US-6020317-A Glycerol derivative, device and pharmaceutical composition NIPPON SHINYAKU CO. LTD. (JP) 2000-02-01 US disclosed
EP-0685457-B1 GLYCEROL DERIVATIVE, DEVICE AND PHARMACEUTICAL COMPOSITION NIPPON SHINYAKU CO LTD (JP) 1999-12-15 EP disclosed
US-5705188-A LIPID MIXTURE, ANTITUMOR AGENTS NIPPON SHINYAKU COMPANY, LTD. (JP) 1998-01-06 US disclosed
EP-0685457-A1 GLYCEROL DERIVATIVE, DEVICE AND PHARMACEUTICAL COMPOSITION NIPPON SHINYAKU COMPANY, LIMITED (JP) 1995-12-06 EP disclosed
EP-0685234-A1 DRUG COMPOSITION CONTAINING NUCLEIC ACID COPOLYMER NIPPON SHINYAKU COMPANY, LIMITED (JP) 1995-12-06 EP disclosed