Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18335360 | 1.00 | FAAH (0.44) | FAAHMGLLCNR1ALDH1A1MAPT | |
| SCHEMBL20609364 | 0.92 | FAAH (0.39) | FAAHMGLLCNR1ALDH1A1MAPT | |
| SCHEMBL18350868 | 0.89 | MGLL (0.50) | FAAHMGLLCNR1ALDH1A1MAPT | |
| SCHEMBL18350872 | 0.88 | FAAH (0.46) | FAAHMGLLCNR1ALDH1A1MAPT | |
| SCHEMBL18003941 | 0.84 | FAAH (0.46) | FAAHMGLLCNR1ALDH1A1MAPT | |
| SCHEMBL18003939 | 0.84 | FAAH (0.46) | FAAHMGLLCNR1ALDH1A1MAPT | |
| SCHEMBL18350867 | 0.84 | DNM1 (0.44) | FAAHMAPTTHRBDNM1 | |
| SCHEMBL18350953 | 0.83 | ALDH1A1 (0.47) | FAAHMGLLCNR1ALDH1A1MAPT | |
| SCHEMBL18350847 | 0.82 | CNR1 (0.48) | MGLLCNR1ALDH1A1THRB | |
| SCHEMBL20609402 | 0.82 | FAAH (0.48) | FAAHMGLLCNR1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250250226-A1 | IONIZABLE COMPOUNDS AND COMPOSITIONS AND USES THEREOF | NITTO DENKO CORP (JP) | 2025-08-07 | — | — | US | disclosed |
| US-12319643-B2 | Ionizable compounds and compositions and uses thereof | NITTO DENKO CORPORATION (JP) | 2025-06-03 | — | — | US | disclosed |
| US-20220242820-A1 | IONIZABLE COMPOUNDS AND COMPOSITIONS AND USES THEREOF | NITTO DENKO CORPORATION (JP) | 2022-08-04 | — | — | US | disclosed |
| US-11384051-B2 | Ionizable compounds and compositions and uses thereof | NITTO DENKO CORPORATION (JP) | 2022-07-12 | — | — | US | disclosed |
| US-11384051-B2 | Ionizable compounds and compositions and uses thereof | NITTO DENKO CORPORATION (JP) | 2022-07-12 | — | — | US | disclosed |
| EP-3313449-B1 | IONIZABLE COMPOUNDS AND COMPOSITIONS AND USES THEREOF | NITTO DENKO CORP (JP) | 2020-09-23 | — | — | EP | disclosed |
| EP-3686184-A2 | IONIZABLE COMPOUNDS AND COMPOSITIONS AND USES THEREOF | NITTO DENKO CORPORATION (JP) | 2020-07-29 | — | — | EP | disclosed |
| EP-3686184-A2 | IONIZABLE COMPOUNDS AND COMPOSITIONS AND USES THEREOF | NITTO DENKO CORPORATION (JP) | 2020-07-29 | — | — | EP | disclosed |
| US-20190127318-A1 | IONIZABLE COMPOUNDS AND COMPOSITIONS AND USES THEREOF | NITTO DENKO CORPORATION (JP) | 2019-05-02 | — | — | US | disclosed |
| US-20190127318-A1 | IONIZABLE COMPOUNDS AND COMPOSITIONS AND USES THEREOF | NITTO DENKO CORPORATION (JP) | 2019-05-02 | — | — | US | disclosed |
| US-10167253-B2 | Ionizable compounds and compositions and uses thereof | NITTO DENKO CORPORATION (JP) | 2019-01-01 | — | — | US | disclosed |
| US-10167253-B2 | Ionizable compounds and compositions and uses thereof | NITTO DENKO CORPORATION (JP) | 2019-01-01 | — | — | US | disclosed |
| EP-3313449-A1 | IONIZABLE COMPOUNDS AND COMPOSITIONS AND USES THEREOF | Nitto Denko Corporation (JP) | 2018-05-02 | — | — | EP | disclosed |
| WO-2016210190-A1 | IONIZABLE COMPOUNDS AND COMPOSITIONS AND USES THEREOF | NITTO DENKO CORPORATION (JP) | 2016-12-29 | — | — | WO | disclosed |
| US-20160376229-A1 | IONIZABLE COMPOUNDS AND COMPOSITIONS AND USES THEREOF | NITTO DENKO CORPORATION (JP) | 2016-12-29 | — | — | US | disclosed |
| US-20160376229-A1 | IONIZABLE COMPOUNDS AND COMPOSITIONS AND USES THEREOF | NITTO DENKO CORPORATION (JP) | 2016-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220242820-A1 | IONIZABLE COMPOUNDS AND COMPOSITIONS AND USES THEREOF | NCL, RNASE1, RNMT | FAAH 4419/4885MGLL 3231/4885CNR1 4186/4885 |
| US-20250250226-A1 | IONIZABLE COMPOUNDS AND COMPOSITIONS AND USES THEREOF | NCL, RNASE1, RNMT | FAAH 4419/4885MGLL 3231/4885CNR1 4186/4885 |
| US-10167253-B2 | Ionizable compounds and compositions and uses thereof | NCL, CHMP4B, RNASE1 | FAAH 3999/4885MGLL 2871/4885CNR1 3674/4885 |
| US-20160376229-A1 | IONIZABLE COMPOUNDS AND COMPOSITIONS AND USES THEREOF | NCL, CHMP4B, RNASE1 | FAAH 3999/4885MGLL 2871/4885CNR1 3674/4885 |
| US-11384051-B2 | Ionizable compounds and compositions and uses thereof | NCL, CHMP4B, RNASE1 | FAAH 3999/4885MGLL 2871/4885CNR1 3674/4885 |
| US-20190127318-A1 | IONIZABLE COMPOUNDS AND COMPOSITIONS AND USES THEREOF | NCL, CHMP4B, RNASE1 | FAAH 3999/4885MGLL 2871/4885CNR1 3674/4885 |
| US-12319643-B2 | Ionizable compounds and compositions and uses thereof | NCL, RNASE1, RNMT | FAAH 4419/4885MGLL 3231/4885CNR1 4186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.