Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | EDNRA | P25101 | 2/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTGIR | P43119 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13163776 | 0.88 | EDNRA (0.54) | ABCG2EDNRALRRK2MTNR1AMTNR1B | |
| SCHEMBL10709610 | 0.82 | MTNR1A (0.57) | ABCG2EDNRAMTNR1AMTNR1BCYP1A2 | |
| SCHEMBL31425668 | 0.82 | ACHE (0.54) | ABCG2EDNRAMTNR1AMTNR1BCYP3A4 | |
| SCHEMBL3164341 | 0.82 | ACHE (0.54) | ABCG2EDNRAMTNR1AMTNR1BCYP3A4 | |
| SCHEMBL24433577 | 0.80 | ACHE (0.52) | ABCG2EDNRAMTNR1AMTNR1BCYP3A4 | |
| SCHEMBL9770219 | 0.79 | HTR2C (0.55) | ABCG2EDNRAMTNR1AMTNR1BCYP1A2 | |
| Anisole SCHEMBL6670370 | 0.78 | CA4 (0.67) | MAPTMEN1KMT2ACA4 | |
| SCHEMBL3484059 | 0.76 | ACHE (0.53) | ABCG2EDNRALRRK2MTNR1AMTNR1B | |
| SCHEMBL31345530 | 0.76 | ACHE (0.53) | ABCG2EDNRALRRK2MTNR1AMTNR1B | |
| SCHEMBL921437 | 0.75 | MTNR1A (0.48) | ABCG2EDNRAMTNR1AMTNR1BCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136425-A | SUITABLE FOR A PRINTING PLATE WHICH GIVES AN EXCELLENT WATER RETENTION PROPERTY AND PREVENTS STAINS FROM OCCURRING AT NON-IMAGE PORTIONS | KONICA CORPORATION (JP) | 2000-10-24 | — | — | US | disclosed |