Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8011476 | 0.88 | MEN1 (0.36) | RAB9ANPC1MAPTKDM4EL3MBTL1 | |
| SCHEMBL8009928 | 0.88 | MAPT (0.38) | RAB9ANPC1MAPTKDM4EL3MBTL1 | |
| SCHEMBL8003707 | 0.88 | RAB9A (0.36) | RAB9ANPC1MAPTKDM4EL3MBTL1 | |
| SCHEMBL7996164 | 0.81 | RAB9A (0.37) | RAB9ANPC1MAPTKDM4EL3MBTL1 | |
| SCHEMBL883446 | 0.80 | MAPT (0.38) | RAB9ANPC1MAPTKDM4EL3MBTL1 | |
| SCHEMBL15216113 | 0.79 | KDM4E (0.42) | MAPTKDM4EL3MBTL1LMNANPSR1 | |
| SCHEMBL11951314 | 0.78 | ALDH1A1 (0.37) | RAB9ANPC1MAPTKDM4EL3MBTL1 | |
| SCHEMBL1952194 | 0.77 | ALDH1A1 (0.36) | RAB9ANPC1MAPTKDM4EL3MBTL1 | |
| SCHEMBL577448 | 0.77 | KDM4E (0.32) | RAB9ANPC1MAPTKDM4EL3MBTL1 | |
| SCHEMBL313502 | 0.75 | ALDH1A1 (0.35) | RAB9ANPC1MAPTKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009099596-A2 | MACROCYCLIC SERINE PROTEASE INHIBITORS | IDENIX PHARAMACEUTICALS, INC. (US) | 2009-08-13 | — | — | WO | disclosed |