Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8005228 | 1.00 | MAOA (0.43) | MAOAMAOBHRH3TSHRHSD17B10 | |
| SCHEMBL8022463 | 0.86 | GRIA2 (0.37) | HRH3SLC6A2SLC6A4 | |
| SCHEMBL8022460 | 0.86 | GRIA2 (0.37) | HRH3SLC6A2SLC6A4 | |
| SCHEMBL10802960 | 0.76 | TSHR (0.56) | MAOAMAOBHRH3TSHRHSD17B10 | |
| SCHEMBL10802955 | 0.76 | TSHR (0.56) | MAOAMAOBHRH3TSHRHSD17B10 | |
| SCHEMBL23588057 | 0.75 | MAOB (0.65) | MAOAMAOBHRH3TSHRHSD17B10 | |
| SCHEMBL11524939 | 0.75 | GRIA2 (0.45) | HRH3SLC6A2SLC6A4 | |
| SCHEMBL11524934 | 0.75 | GRIA2 (0.45) | HRH3SLC6A2SLC6A4 | |
| SCHEMBL9317223 | 0.73 | TSHR (0.52) | MAOAMAOBHRH3TSHRHSD17B10 | |
| SCHEMBL8376586 | 0.73 | TSHR (0.52) | MAOAMAOBHRH3TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670322-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 2000-01-19 | — | — | EP | disclosed |
| US-5582764-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| EP-0670322-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-09-06 | — | — | EP | disclosed |