Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 18/20 | 0.43 |
| ▸ | RXRB | P28702 | 6/20 | 0.43 |
| ▸ | RXRG | P48443 | 6/20 | 0.43 |
| ▸ | RARA | P10276 | 3/20 | 0.43 |
| ▸ | RARB | P10826 | 3/20 | 0.43 |
| ▸ | RARG | P13631 | 3/20 | 0.43 |
| ▸ | HNF4A | P41235 | 8/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8011713 | 0.91 | RXRA (0.41) | RXRARXRBRXRGRARARARB | |
| SCHEMBL8009347 | 0.86 | RXRA (0.41) | RXRARXRBRXRGRARARARB | |
| SCHEMBL6916817 | 0.84 | RXRA (0.46) | RXRARXRBRXRGRARARARB | |
| SCHEMBL6915982 | 0.82 | RXRA (0.41) | RXRARXRBRXRGRARARARB | |
| SCHEMBL8005479 | 0.82 | RXRA (0.46) | RXRARXRBRXRGRARARARB | |
| SCHEMBL6915152 | 0.81 | RXRA (0.36) | RXRARXRBRXRGRARARARB | |
| SCHEMBL7735872 | 0.78 | RXRA (0.52) | RXRARXRBRXRGRARARARB | |
| SCHEMBL7735871 | 0.78 | RXRA (0.52) | RXRARXRBRXRGRARARARB | |
| SCHEMBL7732340 | 0.75 | RXRA (0.45) | RXRARXRBRXRGRARARARB | |
| SCHEMBL7732336 | 0.75 | RXRA (0.45) | RXRARXRBRXRGRARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000026173-A1 | NOVEL RETINOIDS, METHODS FOR THEIR PRODUCTION AND USE | LIGAND PHARMACEUTICALS INCORPORATED (DE) | 2000-05-11 | — | — | WO | disclosed |
| US-6005007-A | SKIN DISORDERS | LIGAND PHARMACEUTICALS INCORPORATED | 1999-12-21 | — | — | US | disclosed |