Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 20/20 | 0.41 |
| ▸ | RXRG | P48443 | 15/20 | 0.41 |
| ▸ | RXRB | P28702 | 14/20 | 0.41 |
| ▸ | RARG | P13631 | 3/20 | 0.37 |
| ▸ | RARB | P10826 | 2/20 | 0.36 |
| ▸ | RARA | P10276 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8011713 | 0.87 | RXRA (0.41) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL8005485 | 0.86 | RXRA (0.43) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL8009343 | 0.80 | RXRA (0.46) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL6916817 | 0.76 | RXRA (0.46) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL8417708 | 0.75 | RXRA (0.52) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL6915982 | 0.74 | RXRA (0.41) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL6915152 | 0.73 | RXRA (0.36) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL7735871 | 0.69 | RXRA (0.52) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL8005479 | 0.69 | RXRA (0.46) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL8011708 | 0.69 | RXRA (0.46) | RXRARXRGRXRBRARGRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000026173-A1 | NOVEL RETINOIDS, METHODS FOR THEIR PRODUCTION AND USE | LIGAND PHARMACEUTICALS INCORPORATED (DE) | 2000-05-11 | — | — | WO | disclosed |
| US-6005007-A | SKIN DISORDERS | LIGAND PHARMACEUTICALS INCORPORATED | 1999-12-21 | — | — | US | disclosed |