Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3797063 | 0.89 | GAA (0.37) | RORCKDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL8005821 | 0.89 | ALDH1A1 (0.39) | RORCKDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL7996164 | 0.88 | RAB9A (0.37) | KDM4EALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL7996053 | 0.82 | KDM4E (0.36) | RORCKDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL577373 | 0.78 | ALDH1A1 (0.35) | KDM4EALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL13090548 | 0.77 | MAPT (0.40) | KDM4EALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL15216114 | 0.77 | GAA (0.38) | KDM4EALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL15216089 | 0.77 | ALDH1A1 (0.38) | KDM4EALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL8135741 | 0.74 | ALDH1A1 (0.39) | KDM4EALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL15692157 | 0.73 | RXFP1 (0.45) | KDM4EALDH1A1NPC1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009099596-A2 | MACROCYCLIC SERINE PROTEASE INHIBITORS | IDENIX PHARAMACEUTICALS, INC. (US) | 2009-08-13 | — | — | WO | disclosed |