Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8017497 | 0.75 | CYP1A2 (0.34) | ALDH1A1BACE1MAPK1 | |
| SCHEMBL8014938 | 0.75 | KIF11 (0.36) | ALDH1A1BACE1 | |
| SCHEMBL8005753 | 0.71 | KIF11 (0.36) | ALDH1A1BACE1 | |
| SCHEMBL20083044 | 0.68 | ALDH1A1 (0.41) | ALDH1A1BACE1MAPK1 | |
| SCHEMBL31497105 | 0.66 | ALDH1A1 (0.47) | ALDH1A1BACE1MAPK1 | |
| SCHEMBL791507 | 0.66 | — | — | |
| SCHEMBL28455859 | 0.58 | ALDH1A1 (0.50) | ALDH1A1BACE1MAPK1 | |
| Biphenyl SCHEMBL7559091 | 0.57 | ALDH1A1 (0.69) | ALDH1A1MAPK1 | |
| Biphenyl SCHEMBL27390314 | 0.57 | ALDH1A1 (0.69) | ALDH1A1MAPK1 | |
| Biphenyl SCHEMBL2548048 | 0.54 | ALDH1A1 (1.00) | ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110947-A | AN ANALGESIC AGENT FOR TREATING STROKE, ABDOMINAL PAIN; AS ANTIINFLAMMATORY, DIURETIC, ANESTHETIC OR NEUROPROTECTIVE AGENTS | PFIZER INC. (US) | 2000-08-29 | — | — | US | disclosed |
| CN-1180348-A | Pyrrolidinyl hydroxamic acid compounds and their production process | PFIZER (US) | 1998-04-29 | — | — | CN | disclosed |