Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8014938 | 0.85 | KIF11 (0.36) | KIF11BACE1ALDH1A1TSHR | |
| SCHEMBL8006370 | 0.71 | ALDH1A1 (0.32) | BACE1ALDH1A1 | |
| SCHEMBL6335738 | 0.71 | — | — | |
| SCHEMBL31497105 | 0.67 | ALDH1A1 (0.47) | BACE1ALDH1A1 | |
| SCHEMBL2752470 | 0.67 | — | — | |
| SCHEMBL8017497 | 0.67 | CYP1A2 (0.34) | BACE1ALDH1A1 | |
| SCHEMBL10401569 | 0.67 | KIF11 (0.36) | KIF11BACE1ALDH1A1TSHR | |
| SCHEMBL6302424 | 0.66 | — | — | |
| SCHEMBL8889982 | 0.66 | — | — | |
| SCHEMBL2749864 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110947-A | AN ANALGESIC AGENT FOR TREATING STROKE, ABDOMINAL PAIN; AS ANTIINFLAMMATORY, DIURETIC, ANESTHETIC OR NEUROPROTECTIVE AGENTS | PFIZER INC. (US) | 2000-08-29 | — | — | US | disclosed |