Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.75 |
| ▸ | MEN1 | O00255 | 6/20 | 0.75 |
| ▸ | MAPT | P10636 | 6/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.75 |
| ▸ | POLB | P06746 | 5/20 | 0.75 |
| ▸ | BLM | P54132 | 5/20 | 0.75 |
| ▸ | RECQL | P46063 | 4/20 | 0.75 |
| ▸ | HPGD | P15428 | 4/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.75 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.75 |
| ▸ | PKM | P14618 | 2/20 | 0.75 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.75 |
| ▸ | CASP1 | P29466 | 2/20 | 0.75 |
| ▸ | CASP7 | P55210 | 2/20 | 0.75 |
| ▸ | TSHR | P16473 | 2/20 | 0.75 |
| ▸ | THRB | P10828 | 3/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27734202 | 0.86 | MEN1 (1.00) | ALDH1A1MEN1MAPTKMT2ATDP1 | |
| SCHEMBL13787415 | 0.79 | ALDH1A1 (0.70) | ALDH1A1MEN1MAPTKMT2ATDP1 | |
| SCHEMBL28079386 | 0.78 | MEN1 (0.81) | ALDH1A1MEN1MAPTKMT2ATDP1 | |
| SCHEMBL503307 | 0.78 | MEN1 (0.75) | ALDH1A1MEN1MAPTKMT2ATDP1 | |
| SCHEMBL28532446 | 0.77 | TDP1 (0.62) | ALDH1A1MEN1MAPTKMT2ATDP1 | |
| SCHEMBL20392752 | 0.75 | ADORA2A (0.52) | ALDH1A1MEN1MAPTKMT2ATDP1 | |
| SCHEMBL6238182 | 0.75 | PIK3R1 (0.66) | ALDH1A1MEN1MAPTKMT2ATDP1 | |
| SCHEMBL6238059 | 0.74 | MAPT (0.62) | ALDH1A1MEN1MAPTKMT2ATDP1 | |
| SCHEMBL7696747 | 0.73 | TDP1 (1.00) | ALDH1A1MEN1MAPTKMT2ATDP1 | |
| SCHEMBL3685471 | 0.73 | ALDH1A1 (0.53) | ALDH1A1MEN1MAPTKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962551-B2 | Quinoxalinyl derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2015-02-24 | — | — | US | disclosed |
| US-20090180981-A1 | QUINOXALINYL DERIVATIVES | ENANTA PHARMACEUTICALS, INC. | 2009-07-16 | — | — | US | disclosed |
| WO-2009073719-A1 | QUINOXALINYL DERIVATIVES | ENANTA PHARMACEUTICALS, INC. (US) | 2009-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090180981-A1 | QUINOXALINYL DERIVATIVES | SQOR, ATG4A, NQO1 | ALDH1A1 746/4885MEN1 4281/4885MAPT 4629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.