SCHEMBL8007002

SCHEMBL8007002

CCc1nc2c(-c3cc(F)c(C)cc3C)cccc2n1C(CC)CC

nearest known ligand 0.44

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7816740 0.86
SCHEMBL7590367 0.80 CRHR1 (0.41)
SCHEMBL7821933 0.77 TLR8 (0.46)
SCHEMBL7813333 0.77
SCHEMBL8007799 0.72
SCHEMBL7036287 0.71
SCHEMBL7038547 0.69
SCHEMBL7106323 0.67
SCHEMBL7027847 0.65
SCHEMBL7033636 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6124463-A TREATMENT OF AFFECTIVE DISORDER, ANXIETY OR DEPRESSION DUPONT PHARMACEUTICALS (US) 2000-09-26 US disclosed