Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.82 |
| ▸ | HPGD | P15428 | 4/20 | 0.82 |
| ▸ | LMNA | P02545 | 1/20 | 0.82 |
| ▸ | NPC1 | O15118 | 5/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.76 |
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.67 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | PPARA | Q07869 | 1/20 | 0.55 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565913 | 0.88 | RAB9A (0.81) | RAB9AHPGDLMNANPC1SMN1; SMN2 | |
| SCHEMBL7565917 | 0.86 | RAB9A (0.72) | RAB9AHPGDLMNANPC1SMN1; SMN2 | |
| SCHEMBL10658594 | 0.85 | LMNA (0.68) | RAB9AHPGDLMNANPC1SMN1; SMN2 | |
| SCHEMBL882828 | 0.85 | RAB9A (0.72) | RAB9AHPGDLMNANPC1SMN1; SMN2 | |
| SCHEMBL12285188 | 0.84 | RAB9A (0.74) | RAB9AHPGDLMNANPC1SMN1; SMN2 | |
| SCHEMBL13665249 | 0.84 | RAB9A (0.78) | RAB9AHPGDLMNANPC1SMN1; SMN2 | |
| SCHEMBL30444388 | 0.84 | HPGD (0.61) | RAB9AHPGDLMNANPC1SMN1; SMN2 | |
| SCHEMBL3765824 | 0.84 | RAB9A (0.69) | RAB9AHPGDLMNANPC1SMN1; SMN2 | |
| SCHEMBL10192011 | 0.83 | RAB9A (0.72) | RAB9AHPGDLMNANPC1SMN1; SMN2 | |
| SCHEMBL27422626 | 0.83 | RAB9A (0.72) | RAB9AHPGDLMNANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773950-A4 | LINKED PEPTIDE NUCLEIC ACIDS | ISIS PHARMACEUTICALS INC (US) | 2000-05-17 | — | — | EP | disclosed |
| EP-0773950-A1 | LINKED PEPTIDE NUCLEIC ACIDS | ISIS PHARMACEUTICALS, INC. (US) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996002558-A1 | LINKED PEPTIDE NUCLEIC ACIDS | ISIS PHARMACEUTICALS, INC. (US) | 1996-02-01 | — | — | WO | disclosed |