Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.48 |
| ▸ | HTR2A | P28223 | 5/20 | 0.48 |
| ▸ | HTR2B | P41595 | 4/20 | 0.48 |
| ▸ | KMO | O15229 | 7/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8013345 | 0.83 | HTR2A (0.52) | HTR2CHTR2AHTR2BKMOCYP1A2 | |
| Ammonia Solution, Strong SCHEMBL906042 | 0.83 | KMO (0.42) | HTR2CHTR2AHTR2BKMOCYP1A2 | |
| SCHEMBL906040 | 0.78 | HTR2A (0.60) | HTR2CHTR2AHTR2BKMOHTR1A | |
| SCHEMBL3243999 | 0.77 | CYP1A2 (0.58) | HTR2CHTR2AHTR2BKMOP2RX7 | |
| SCHEMBL8007547 | 0.75 | HTR2A (0.55) | HTR2CHTR2AHTR2BKMOP2RX7 | |
| SCHEMBL8009717 | 0.71 | KMO (0.40) | HTR2CHTR2AHTR2BKMOHTR1A | |
| SCHEMBL16573725 | 0.69 | MEN1 (0.35) | HTR2CHTR2AHTR2BHTR1A | |
| SCHEMBL29355368 | 0.69 | CYP1A2 (0.45) | HTR2CHTR2AHTR2BKMOP2RX7 | |
| SCHEMBL906041 | 0.68 | SLC6A4 (0.36) | HTR2CHTR2AHTR2BKMOHTR6 | |
| SCHEMBL20083661 | 0.67 | CYP1A2 (0.62) | HTR2CHTR2AHTR2BKMOP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000017170-A2 | N1-SUBSTITUTED BENZOPYRAZOLES AS INHIBITORS OF 5-HT2 RECEPTORS | VERNALIS RESEARCH LIMITED (GB) | 2000-03-30 | — | — | WO | disclosed |