SCHEMBL8007208

SCHEMBL8007208

CN(C)Cc1ccc(S)o1

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ACHE P22303 15/20 0.55
BCHE P06276 10/20 0.52
PRMT6 Q96LA8 1/20 0.46
CYP2A6 P11509 1/20 0.42
CYP2C19 P33261 1/20 0.42
MYC P01106 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2458150 0.83 ACHE (0.74) ACHEBCHEPRMT6CYP2A6CYP2C19
SCHEMBL8409986 0.77 ACHE (0.61) ACHEBCHEPRMT6CYP2A6CYP2C19
SCHEMBL14288615 0.76 ACHE (0.59) ACHEBCHEPRMT6CYP2A6CYP2C19
SCHEMBL82414 0.74 POLB (0.59) ACHEBCHEPRMT6
SCHEMBL12655116 0.74 ACHE (0.63) ACHEBCHEPRMT6CYP2A6CYP2C19
SCHEMBL7998986 0.74 ACHE (0.57) ACHEBCHEPRMT6CYP2A6CYP2C19
SCHEMBL613164 0.73 ACHE (0.55) ACHEBCHEPRMT6CYP2A6CYP2C19
SCHEMBL8610492 0.73 ACHE (0.61) ACHEBCHEPRMT6CYP2A6CYP2C19
SCHEMBL9839086 0.73 ACHE (0.61) ACHEBCHEPRMT6CYP2A6CYP2C19
SCHEMBL6419073 0.73 ACHE (0.55) ACHEBCHEPRMT6CYP2A6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000029400-A2 PROCEDURE FOR SYNTHESIS OF N-[2[[[5- [(DIALKILAMINO) METHYL]-2- FURANYL] METHYL]THYO] ETHYL]-N'- ALKYL-2-NITRO1,1 ALKENEDIAMINES AND THEIR HYDROCHLORIDES DD'ZDRAVLJE'- FARMACEUTSKO-HEMIJSKA INDUSTRIJA D.D. U. MEŠOVITOJ SVOJINI (YU) 2000-05-25 WO disclosed