SCHEMBL82414

SCHEMBL82414

Cc1ccc(CN(C)C)o1

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.59
ACHE P22303 12/20 0.57
BCHE P06276 9/20 0.53
ALOX5 P09917 1/20 0.53
MEN1 O00255 1/20 0.50
CHRM2 P08172 1/20 0.50
CHRM4 P08173 1/20 0.50
CHRM5 P08912 1/20 0.50
CHRM1 P11229 1/20 0.50
CYP2C9 P11712 1/20 0.50
CHRM3 P20309 1/20 0.50
KMT2A Q03164 1/20 0.50
MAPT P10636 1/20 0.48
PRMT6 Q96LA8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13453301 0.86 POLB (0.59) POLBACHEBCHEALOX5MEN1
SCHEMBL2458150 0.85 ACHE (0.74) ACHEBCHEPRMT6
SCHEMBL8633227 0.77 POLB (0.71) POLBALOX5MEN1CHRM2CHRM4
SCHEMBL12655116 0.76 ACHE (0.63) ACHEBCHEPRMT6
SCHEMBL4999409 0.74 ACHE (0.61) ACHEBCHEPRMT6
SCHEMBL8007208 0.74 ACHE (0.55) ACHEBCHEPRMT6
SCHEMBL8011063 0.74 ACHE (0.61) ACHEBCHEPRMT6
SCHEMBL613164 0.74 ACHE (0.55) ACHEBCHEPRMT6
SCHEMBL6419073 0.74 ACHE (0.55) ACHEBCHEPRMT6
SCHEMBL8409986 0.74 ACHE (0.61) ACHEBCHEPRMT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112142582-A Synthetic method of methyl cyclopentenolone 上海应用技术大学 2020-12-29 CN claimed
CN-106565642-A Synthesis method of N,N-dimethyl-5-methylfurfurylamine 广州百花香料股份有限公司 2017-04-19 CN claimed
US-20050124614-A1 3,4-Dihydroisoquinolin-1-one derivatives as inducers of apoptosis AXYS PHARMACEUTICALS, INC. (US) 2005-06-09 US claimed
WO-2004004727-A1 3,4-DIHYDROISOQUINOLIN-1-ONE DERIVATIVES AS INDUCERS OF APOPTOSIS AXYS PHARMACEUTICALS, INC. (US) 2004-01-15 WO claimed
US-5212187-A Antihistamines ZYMA SA (CH) 1993-05-18 US claimed
EP-0526395-A1 Arylalkylamine derivatives, process for their preparation and pharmaceutical compositions containing them Zyma SA (CH) 1993-02-03 EP claimed
US-4710498-A ANTIULCER AGENTS IKEDA MOHANDO CO., LTD. (JP) 1987-12-01 US claimed
CN-119614200-A Titanium nitride/tungsten etching solution with long service life and high selectivity 湖北兴福电子材料股份有限公司 2025-03-14 CN disclosed
EP-1656983-B1 Process for deacidification of a gas with an absorbing solution and fractional regeneration IFP ENERGIES NOW (FR) 2024-01-24 EP disclosed
EP-3324977-B1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS ENANTA PHARM INC (US) 2022-07-13 EP disclosed
US-11384078-B2 5,6-fused-bicyclic compounds and compositions for the treatment of parasitic diseases NOVARTIS AG (CH) 2022-07-12 US disclosed
US-10881666-B2 Combination pharmaceutical agents as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2021-01-05 US disclosed
CN-112142582-A Synthetic method of methyl cyclopentenolone 上海应用技术大学 2020-12-29 CN disclosed
EP-0177016-B1 PYRIDYLOXY DERIVATIVES Ikeda Mohando Co., Ltd. (JP) 1993-06-23 EP disclosed
US-5212187-A Antihistamines ZYMA SA (CH) 1993-05-18 US disclosed
EP-0526395-A1 Arylalkylamine derivatives, process for their preparation and pharmaceutical compositions containing them Zyma SA (CH) 1993-02-03 EP disclosed
EP-0478195-A1 Dihydropyridazinones, pyridazinones and related compounds as fungicides ROHM AND HAAS COMPANY (US) 1992-04-01 EP disclosed
EP-0437480-A4 METHOD AND APPARATUS FOR CONTINUOUS CHEMICAL REACTIONS 1991-10-30 EP disclosed
EP-0437480-A1 METHOD AND APPARATUS FOR CONTINUOUS CHEMICAL REACTIONS. COMMW SCIENT IND RES ORG (AU) 1991-07-24 EP disclosed
WO-1990003840-A1 METHOD AND APPARATUS FOR CONTINUOUS CHEMICAL REACTIONS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1990-04-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11384078-B2 5,6-fused-bicyclic compounds and compositions for the treatment of parasitic diseases IL5, CYP3A5, ABCB11 POLB 4529/4885ACHE 353/4885BCHE 298/4885
US-10881666-B2 Combination pharmaceutical agents as RSV inhibitors SERPINB1, FURIN, HIF1AN POLB 3263/4885ACHE 4676/4885BCHE 3624/4885
US-20050124614-A1 3,4-Dihydroisoquinolin-1-one derivatives as inducers of apoptosis CASP3, BAX, BAD POLB 2345/4885ACHE 3732/4885BCHE 3416/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.