Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8007310 | 1.00 | MEN1 (0.52) | MEN1KMT2AALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL9658191 | 0.82 | CA12 (0.52) | ALDH1A1PARP1NPC1RAB9AMAPT | |
| SCHEMBL9658196 | 0.82 | CA12 (0.52) | ALDH1A1PARP1NPC1RAB9AMAPT | |
| SCHEMBL8007984 | 0.81 | TSHR (0.48) | MEN1KMT2AALDH1A1CYP2C19NPC1 | |
| SCHEMBL3689392 | 0.81 | TSHR (0.48) | MEN1KMT2AALDH1A1CYP2C19NPC1 | |
| SCHEMBL3958996 | 0.81 | TSHR (0.48) | MEN1KMT2AALDH1A1CYP2C19NPC1 | |
| SCHEMBL8020213 | 0.81 | PKM (0.50) | MEN1KMT2AALDH1A1PARP1HPGD | |
| SCHEMBL9661058 | 0.81 | CES2 (0.59) | MEN1KMT2AALDH1A1PARP1NPC1 | |
| SCHEMBL8020210 | 0.81 | PKM (0.50) | MEN1KMT2AALDH1A1PARP1HPGD | |
| SCHEMBL9661064 | 0.81 | CES2 (0.59) | MEN1KMT2AALDH1A1PARP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675133-B1 | 13-Substituted milbemycin derivatives, their preparation and use | SANKYO CO (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-5614470-A | AGRICULTURAL ANTHELMINTIC, ACARICIDE, INSECTICIDE | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0675133-A1 | 13-Substituted milbemycin derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1995-10-04 | — | — | EP | disclosed |