Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 9/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.72 |
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | AHR | P35869 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22926420 | 0.84 | MEN1 (1.00) | HTTMEN1KMT2AMAPTPOLB | |
| SCHEMBL30051982 | 0.83 | MEN1 (0.77) | HTTMEN1KMT2AMAPTKDM4E | |
| SCHEMBL9637653 | 0.83 | MEN1 (0.77) | HTTMEN1KMT2AMAPTKDM4E | |
| SCHEMBL8016725 | 0.83 | HTT (0.71) | HTTMEN1KMT2AMAPTPOLB | |
| SCHEMBL10665495 | 0.82 | RAB9A (0.79) | HTTMEN1KMT2AMAPTKDM4E | |
| SCHEMBL1700678 | 0.82 | MEN1 (0.87) | HTTMEN1KMT2AMAPTPOLB | |
| SCHEMBL17079604 | 0.82 | MEN1 (0.74) | HTTMEN1KMT2AMAPTKDM4E | |
| SCHEMBL824577 | 0.82 | KMT2A (0.69) | HTTMEN1KMT2AMAPTPOLB | |
| Bromide SCHEMBL29417998 | 0.82 | MEN1 (0.74) | HTTMEN1KMT2AMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL29388210 | 0.82 | MEN1 (0.74) | HTTMEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210022340-A1 | USE OF PYRIDINE UREA COMPOUND HAVING SNAIL-KILLING ACTIVITY | THE NATIONAL INSTITUTE OF PARASITIC DISEASES, CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION (CN) | 2021-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210022340-A1 | USE OF PYRIDINE UREA COMPOUND HAVING SNAIL-KILLING ACTIVITY | SLC14A1, UACA, UROD | HTT 4212/4885MEN1 3057/4885KMT2A 4029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.