Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097375 | 0.85 | OPRL1 (0.46) | OPRD1OPRL1CA12CA1CA2 | |
| SCHEMBL8104825 | 0.79 | OPRM1 (0.45) | OPRD1OPRL1CA12CA1CA2 | |
| SCHEMBL13887044 | 0.79 | MEN1 (0.46) | OPRD1OPRL1CA12CA1CA2 | |
| SCHEMBL1558648 | 0.75 | MEN1 (0.51) | OPRD1OPRL1CA12CA1CA2 | |
| SCHEMBL1558649 | 0.75 | MEN1 (0.51) | OPRD1OPRL1CA12CA1CA2 | |
| SCHEMBL11703497 | 0.73 | MEN1 (0.43) | OPRD1OPRL1CA12CA1CA2 | |
| SCHEMBL8107113 | 0.71 | OPRL1 (0.46) | OPRD1OPRL1CA12CA1CA2 | |
| SCHEMBL14491853 | 0.70 | KDM1A (0.47) | OPRD1OPRL1KMT2AOPRM1HSD11B1 | |
| SCHEMBL17985301 | 0.70 | KDM1A (0.47) | OPRD1OPRL1KMT2AOPRM1HSD11B1 | |
| SCHEMBL8007148 | 0.70 | OPRM1 (0.38) | OPRD1OPRL1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060484-A | Anti-viral method | ELI LILLY AND COMPANY (US) | 2000-05-09 | — | — | US | disclosed |
| WO-1997041846-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1997-11-13 | — | — | WO | disclosed |
| EP-0806205-A2 | Urea, thiourea and guanidine compounds and their use as anti-viral agents | ELI LILLY AND COMPANY (US) | 1997-11-12 | — | — | EP | disclosed |