Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097373 | 0.84 | OPRM1 (0.45) | OPRM1OPRD1CA12CA1CA2 | |
| SCHEMBL8104825 | 0.81 | OPRM1 (0.45) | OPRM1OPRD1CA12CA1CA2 | |
| SCHEMBL13163312 | 0.75 | MEN1 (0.48) | OPRM1OPRD1CA12CA1CA2 | |
| SCHEMBL11473105 | 0.74 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL5370161 | 0.72 | MEN1 (0.43) | OPRM1OPRD1CA12CA1CA2 | |
| SCHEMBL735798 | 0.70 | MEN1 (0.57) | OPRM1OPRD1CA12CA1CA2 | |
| SCHEMBL8007497 | 0.70 | OPRD1 (0.43) | OPRM1OPRD1CA12CA1CA2 | |
| SCHEMBL647137 | 0.69 | CTSK (0.36) | ALDH1A1 | |
| SCHEMBL432561 | 0.68 | OPRM1 (0.59) | OPRM1OPRD1CA12CA1CA2 | |
| Ethylene SCHEMBL3968375 | 0.68 | MEN1 (0.53) | OPRM1OPRD1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060484-A | Anti-viral method | ELI LILLY AND COMPANY (US) | 2000-05-09 | — | — | US | disclosed |
| WO-1997041846-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1997-11-13 | — | — | WO | disclosed |
| EP-0806205-A2 | Urea, thiourea and guanidine compounds and their use as anti-viral agents | ELI LILLY AND COMPANY (US) | 1997-11-12 | — | — | EP | disclosed |