Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13887044 | 0.85 | MEN1 (0.46) | OPRL1CA12CA1CA2CA9 | |
| SCHEMBL8007497 | 0.85 | OPRD1 (0.43) | OPRL1CA12CA1CA2CA9 | |
| SCHEMBL11703497 | 0.83 | MEN1 (0.43) | OPRL1CA12CA1CA2CA9 | |
| SCHEMBL25382786 | 0.81 | WDR5 (0.35) | OPRL1OPRM1 | |
| SCHEMBL12020612 | 0.81 | OPRM1 (0.50) | OPRL1OPRM1KMT2AMAOBMAOA | |
| SCHEMBL1557855 | 0.81 | MAOB (0.41) | NPC1ALDH1A1RAB9ASMN1; SMN2MAOB | |
| SCHEMBL17985304 | 0.81 | MAOB (0.41) | NPC1ALDH1A1RAB9ASMN1; SMN2MAOB | |
| SCHEMBL1003372 | 0.81 | OPRM1 (0.50) | OPRL1OPRM1KMT2AMAOBMAOA | |
| SCHEMBL1558649 | 0.81 | MEN1 (0.51) | OPRL1CA12CA1CA2CA9 | |
| SCHEMBL1558648 | 0.81 | MEN1 (0.51) | OPRL1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124354-A | TREATMENT OF URINARY INCONTINENCE OR IRRITABLE BOWEL SYNDROME | PHARMACIA & UPJOHN AB (SE) | 2000-09-26 | — | — | US | disclosed |