Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 10/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8003719 | 0.84 | METAP2 (0.45) | PARP1MTNR1AMTNR1BCCR1 | |
| SCHEMBL7583585 | 0.80 | PARP1 (0.43) | PARP1MTNR1AMTNR1B | |
| SCHEMBL7774860 | 0.77 | KMT2A (0.38) | MTNR1AMTNR1B | |
| SCHEMBL7590773 | 0.76 | KDM4E (0.41) | PDE10A | |
| SCHEMBL7588354 | 0.74 | MTNR1A (0.39) | MTNR1AMTNR1BPDE4D | |
| SCHEMBL9204288 | 0.72 | PARP1 (0.55) | PARP1MTNR1AMTNR1BPDE10APDE4D | |
| SCHEMBL7583319 | 0.72 | PDE10A (0.43) | PDE10A | |
| SCHEMBL8406965 | 0.70 | EED (0.37) | — | |
| SCHEMBL8003234 | 0.69 | PARP1 (0.46) | PARP1PDE10APDE4DCCR1 | |
| SCHEMBL8003231 | 0.69 | PARP1 (0.46) | PARP1PDE10APDE4DCCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000015617-A1 | 2-AMINOETHYL-QUINOLINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE | SANOFI-SYNTHELABO (FR) | 2000-03-23 | — | — | WO | disclosed |