Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 9/20 | 0.44 |
| ▸ | RXRB | P28702 | 4/20 | 0.38 |
| ▸ | RXRG | P48443 | 3/20 | 0.38 |
| ▸ | RARA | P10276 | 2/20 | 0.38 |
| ▸ | RARB | P10826 | 2/20 | 0.38 |
| ▸ | RARG | P13631 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 6/20 | 0.35 |
| ▸ | POLA1 | P09884 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15348324 | 0.74 | RXRA (0.51) | RXRARXRBRXRGRARARARB | |
| SCHEMBL7713216 | 0.72 | ALDH1A1 (0.55) | RXRARXRBRXRGRARARARB | |
| SCHEMBL8008022 | 0.70 | RXRA (0.39) | RXRARXRBRXRGRARARARB | |
| SCHEMBL5359395 | 0.69 | RXRA (0.75) | RXRARXRBRXRGRARARARB | |
| SCHEMBL24765632 | 0.69 | ALDH1A1 (0.60) | HTR2AHTR2C | |
| SCHEMBL6017468 | 0.69 | RXRA (0.43) | RXRARXRBRXRGRARARARB | |
| SCHEMBL8293241 | 0.68 | RXRA (0.51) | RXRARXRBRXRGRARARARB | |
| SCHEMBL8421087 | 0.67 | RXRA (0.41) | RXRARXRBRXRGRARARARB | |
| SCHEMBL5366510 | 0.66 | RXRA (0.45) | RXRARXRBRXRGRARARARB | |
| SCHEMBL8704549 | 0.65 | RXRA (0.71) | RXRARXRBRXRGRARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000026173-A1 | NOVEL RETINOIDS, METHODS FOR THEIR PRODUCTION AND USE | LIGAND PHARMACEUTICALS INCORPORATED (DE) | 2000-05-11 | — | — | WO | disclosed |
| US-6005007-A | SKIN DISORDERS | LIGAND PHARMACEUTICALS INCORPORATED | 1999-12-21 | — | — | US | disclosed |