SCHEMBL8008079

SCHEMBL8008079

COC(=O)C(=Cc1ccccc1)NC(=O)CN

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.46
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
KDM4E B2RXH2 2/20 0.43
ALDH1A1 P00352 2/20 0.43
HPGD P15428 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
RECQL P46063 1/20 0.41
AKR1C3 P42330 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7997621 0.90 LMNA (0.41) LMNAMEN1KMT2AKDM4EALDH1A1
SCHEMBL7522147 0.88 MEN1 (0.47) LMNAMEN1KMT2AKDM4EALDH1A1
SCHEMBL9488339 0.84 LMNA (0.46) LMNAMEN1KMT2AKDM4EALDH1A1
SCHEMBL9488336 0.84 LMNA (0.46) LMNAMEN1KMT2AKDM4EALDH1A1
SCHEMBL186729 0.82 MEN1 (0.56) LMNAMEN1KMT2AKDM4EALDH1A1
SCHEMBL12394376 0.82 LMNA (0.49) LMNAMEN1KMT2AKDM4EALDH1A1
SCHEMBL187458 0.82 MEN1 (0.56) LMNAMEN1KMT2AKDM4EALDH1A1
SCHEMBL3682708 0.82 MEN1 (0.56) LMNAMEN1KMT2AKDM4EALDH1A1
SCHEMBL9823927 0.80 KMT2A (0.46) LMNAMEN1KMT2AKDM4EALDH1A1
SCHEMBL9487033 0.80 LMNA (0.51) LMNAMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0713859-B1 Cinnamic acid derivatives, photocrosslinkable cinnamic acid-polymer derivative and crosslinked cinnamic acid polymer derivatives SEIKAGAKU KOGYO CO LTD (JP) 2000-08-30 EP disclosed
US-6107410-A Cinnamic acid derivative SEIKAGAKU CORPORATION (JP) 2000-08-22 US disclosed
US-6025444-A HYALURONIC ACID POLYSACCHARIDE DERIVATIVE; PHOTODIMERIZABLE, CROSSLINKABLE SEIKAGAKU KOGYO KABUSHIKI KAISHA (SEIKAGAKU CORPORATION) (JP) 2000-02-15 US disclosed
US-6022924-A OLEFIN OR STYRENIC RESIN; METAL SALT OF FATTY ACID; CARBON BLACK COATED WITH AN ALIPHATIC MONOCARBOXYLIC ACID HAVING A NUMBER OF CARBON ATOMS OF 20 TO 40 AND A MONOVALENT ALIPHATIC ALCOHOL HAVING A NUMBER OF CARBON ATOMS OF 20 TO 40 FUJI PHOTO FILM CO., LTD. (JP) 2000-02-08 US disclosed
EP-0713859-A2 Cinnamic acid derivatives, photocrosslinkable cinnamic acid-polymer derivative and crosslinked cinnamic acid polymer derivatives SEIKAGAKU KOGYO KABUSHIKI KAISHA (SEIKAGAKU CORPORATION) (JP) 1996-05-29 EP disclosed