Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187458 | 0.84 | MEN1 (0.56) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL186729 | 0.84 | MEN1 (0.56) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL3682708 | 0.84 | MEN1 (0.56) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL12394376 | 0.81 | LMNA (0.49) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7522147 | 0.80 | MEN1 (0.47) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8008079 | 0.80 | LMNA (0.46) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9488339 | 0.80 | LMNA (0.46) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9488336 | 0.80 | LMNA (0.46) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7642884 | 0.78 | LMNA (0.69) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL20223419 | 0.77 | ITGB1 (0.47) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3153653-A | — | — | None | — | — | JP | disclosed |
| JP-H03153653-A | N-(1-ALKOXYCARBONYLSTYRYL)FUMARAMIC ACID AND PRODUCTION THEREOF | KURARAY CO LTD | 1991-07-01 | — | — | JP | disclosed |