Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 12/20 | 0.40 |
| ▸ | NOS3 | P29474 | 6/20 | 0.40 |
| ▸ | NOS1 | P29475 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15498161 | 0.85 | NOS2 (0.62) | NOS2NOS3NOS1 | |
| SCHEMBL8019875 | 0.78 | GABRA1 (0.37) | TSHR | |
| SCHEMBL15498160 | 0.73 | UHRF1 (0.46) | NOS2NOS3NOS1ALDH1A1 | |
| SCHEMBL20201756 | 0.72 | ESR1 (0.31) | — | |
| SCHEMBL21325539 | 0.72 | GRN (0.32) | — | |
| SCHEMBL2476938 | 0.72 | KCNH2 (0.41) | NOS2NOS1 | |
| SCHEMBL28416688 | 0.72 | NOS2 (0.47) | NOS2NOS3NOS1 | |
| SCHEMBL18501679 | 0.72 | HMGCR (0.32) | — | |
| SCHEMBL6464978 | 0.70 | NOS2 (0.70) | NOS2NOS3NOS1 | |
| SCHEMBL16673269 | 0.70 | ESR1 (0.44) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6087461-A | SILANE COMPOUNDS AND ENDBLOCKING POLYMERS | DOW CORNING LIMITED (GB) | 2000-07-11 | — | — | US | disclosed |
| EP-0887358-A1 | Process for making silyl endblocked organic polymers | DOW CORNING LIMITED (GB) | 1998-12-30 | — | — | EP | disclosed |