Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 11/20 | 0.70 |
| ▸ | NOS3 | P29474 | 6/20 | 0.70 |
| ▸ | NOS1 | P29475 | 7/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20072591 | 0.88 | NOS2 (0.57) | NOS2NOS3NOS1 | |
| SCHEMBL7116565 | 0.87 | NOS2 (0.61) | NOS2NOS3NOS1 | |
| SCHEMBL12250784 | 0.84 | NOS2 (0.63) | NOS2NOS3NOS1ESR1 | |
| SCHEMBL23280308 | 0.83 | NOS2 (0.57) | NOS2NOS3NOS1 | |
| SCHEMBL13827864 | 0.83 | NOS2 (0.57) | NOS2NOS3NOS1ESR1 | |
| SCHEMBL18611531 | 0.83 | NOS2 (0.57) | NOS2NOS3NOS1 | |
| SCHEMBL7049604 | 0.83 | NOS2 (1.00) | NOS2NOS3NOS1 | |
| SCHEMBL9130357 | 0.83 | NOS2 (0.57) | NOS2NOS3NOS1ESR1 | |
| SCHEMBL12250803 | 0.79 | NOS2 (0.53) | NOS2NOS3NOS1 | |
| SCHEMBL12574412 | 0.79 | NOS2 (0.53) | NOS2NOS3NOS1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021064332-A1 | ANTI-CD30-DRUG CONJUGATES AND THEIR USE IN THERAPY | MC SAF (FR) | 2021-04-08 | — | — | WO | disclosed |
| WO-2020234541-A1 | ANTIBODY-DRUG CONJUGATES AND THEIR USE IN THERAPY | MC SAF (FR) | 2020-11-26 | — | — | WO | disclosed |
| US-20140030223-A1 | INHIBITORS OF FLAVIVIRIDAE VIRUSES | GILEAD SCIENCES, INC. (US) | 2014-01-30 | — | — | US | disclosed |
| US-20140030223-A1 | INHIBITORS OF FLAVIVIRIDAE VIRUSES | GILEAD SCIENCES, INC. (US) | 2014-01-30 | — | — | US | disclosed |
| US-8569302-B2 | Inhibitors of flaviviridae viruses | GILEAD SCIENCES, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-8569302-B2 | Inhibitors of flaviviridae viruses | GILEAD SCIENCES, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-20120104941-A1 | COMPOUND FOR AN ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME | CHEIL INDUSTRIES, INC. (KR) | 2012-05-03 | — | — | US | disclosed |
| US-20110212998-A1 | PYRIDINE DERIVATIVES AS S1P1/EDG1 RECEPTOR MODULATORS | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-09-01 | — | — | US | disclosed |
| US-20110212998-A1 | PYRIDINE DERIVATIVES AS S1P1/EDG1 RECEPTOR MODULATORS | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-09-01 | — | — | US | disclosed |
| EP-2195311-B1 | PYRIDINE DERIVATIVES AS S1P1/EDG1 RECEPTOR MODULATORS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-03-23 | — | — | EP | disclosed |
| US-20110020278-A1 | INHIBITORS OF FLAVIVIRIDAE VIRUSES | GILEAD SCIENCES, INC. (US) | 2011-01-27 | — | — | US | disclosed |
| US-20110020278-A1 | INHIBITORS OF FLAVIVIRIDAE VIRUSES | GILEAD SCIENCES, INC. (US) | 2011-01-27 | — | — | US | disclosed |
| WO-2011011303-A1 | INHIBITORS OF FLAVIVIRIDAE VIRUSES | GILEAD SCIENCES, INC. (US) | 2011-01-27 | — | — | WO | disclosed |
| US-20100022664-A1 | Process for the partial hydrogenation of fatty acid esters | COGNIS IP MANAGEMENT GMBH (DE) | 2010-01-28 | — | — | US | disclosed |
| WO-2009024905-A1 | PYRIDINE DERIVATIVES AS S1P1/EDG1 RECEPTOR MODULATORS | ACTELION PHARMACEUTICALS LTD (CH) | 2009-02-26 | — | — | WO | disclosed |
| US-20050075241-A1 | Catalyst systems of the ziegler-natta type and a method for production thereof | FOTTINGER KLAUS (DE) | 2005-04-07 | — | — | US | disclosed |
| EP-1445260-A1 | Method of immobilising of chemical compounds to solid phases | Jerini AG (DE) | 2004-08-11 | — | — | EP | disclosed |
| EP-1326899-A2 | CATALYTIC SYSTEMS OF THE ZIEGLER-NATTA TYPE AND METHOD FOR PRODUCTION THEREOF | Basell Polyolefine GmbH (DE) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002032969-A2 | CATALYTIC SYSTEMS OF THE ZIEGLER-NATTA TYPE AND METHOD FOR PRODUCTION THEREOF | BASELL POLYOLEFINE GMBH (DE) | 2002-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140030223-A1 | INHIBITORS OF FLAVIVIRIDAE VIRUSES | HAVCR2, CYP2F1, CYP4F3 | NOS2 3198/4885NOS3 2330/4885NOS1 2809/4885 |
| US-20100022664-A1 | Process for the partial hydrogenation of fatty acid esters | ELOVL3, LIPA, FFAR2 | NOS2 667/4885NOS3 1262/4885NOS1 1656/4885 |
| US-20120104941-A1 | COMPOUND FOR AN ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME | PPOX, TYR, VDAC3 | NOS2 2259/4885NOS3 1376/4885NOS1 2366/4885 |
| US-20110020278-A1 | INHIBITORS OF FLAVIVIRIDAE VIRUSES | HAVCR2, CYP2F1, CYP4F3 | NOS2 3198/4885NOS3 2330/4885NOS1 2809/4885 |
| US-20110212998-A1 | PYRIDINE DERIVATIVES AS S1P1/EDG1 RECEPTOR MODULATORS | S1PR1, S1PR3, S1PR2 | NOS2 2411/4885NOS3 2145/4885NOS1 1194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.