Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CCR4 | P51679 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12051879 | 0.83 | TDP1 (0.34) | TDP1 | |
| SCHEMBL22211759 | 0.80 | HSP90AA1 (0.35) | TDP1KDM4E | |
| SCHEMBL12570324 | 0.78 | NOS3 (0.48) | NOS3NOS1NOS2TSHRCCR4 | |
| SCHEMBL10236287 | 0.77 | NOS3 (0.43) | TDP1NOS3NOS1NOS2TSHR | |
| SCHEMBL22624090 | 0.77 | — | — | |
| SCHEMBL19143739 | 0.77 | TDP1 (0.33) | TDP1 | |
| SCHEMBL27756269 | 0.76 | NPC1 (0.32) | — | |
| SCHEMBL1511034 | 0.76 | ALDH1A1 (0.35) | TDP1TSHRKDM4E | |
| SCHEMBL2476935 | 0.74 | NOS3 (0.34) | NOS3NOS1NOS2TSHRCCR4 | |
| SCHEMBL24917151 | 0.74 | RAB9A (0.34) | TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140163-A1 | OXAZOLOBENZIMIDAZOLE DERIVATIVES | MERCK & CO., INC. (US) | 2009-11-19 | — | — | WO | disclosed |