Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7330565 | 0.99 | RAB9A (0.55) | RAB9ASMN1; SMN2MAPK1NPC1MAPT | |
| SCHEMBL2294574 | 0.86 | MAOB (0.65) | RAB9ASMN1; SMN2NPC1MAPTL3MBTL1 | |
| SCHEMBL3493914 | 0.84 | RAB9A (0.58) | RAB9ASMN1; SMN2MAPK1NPC1MAPT | |
| SCHEMBL2008979 | 0.83 | MAPK1 (0.56) | RAB9ASMN1; SMN2MAPK1NPC1MAPT | |
| SCHEMBL2006466 | 0.83 | MAPK1 (0.56) | RAB9ASMN1; SMN2MAPK1NPC1MAPT | |
| SCHEMBL7334309 | 0.83 | NPC1 (0.49) | RAB9ASMN1; SMN2MAPK1NPC1MAPT | |
| SCHEMBL2013045 | 0.83 | SMN1; SMN2 (0.49) | RAB9ASMN1; SMN2MAPK1NPC1MAPT | |
| SCHEMBL8013977 | 0.82 | ALOX15 (0.61) | RAB9ASMN1; SMN2MAPK1NPC1MAPT | |
| SCHEMBL8681578 | 0.80 | ALDH1A1 (0.61) | RAB9ASMN1; SMN2MAPK1NPC1MAPT | |
| SCHEMBL14405820 | 0.79 | GAA (0.59) | RAB9ASMN1; SMN2MAPK1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028087-A | Platelet aggregation inhibiting compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-22 | — | — | US | disclosed |