Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.35 |
| ▸ | KCNJ1 | P48048 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 5/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 8/20 | 0.34 |
| ▸ | FNTB | P49356 | 7/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 5/20 | 0.33 |
| ▸ | DNAJA1 | P31689 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 4/20 | 0.32 |
| ▸ | HTR2A | P28223 | 4/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6412083 | 0.90 | HTR1A (0.32) | KCNH2HTR1AHTR1DHTR1BFNTA | |
| SCHEMBL6430353 | 0.84 | FNTA (0.48) | FNTAFNTBPGGT1B | |
| SCHEMBL6412080 | 0.73 | FNTA (0.44) | FNTAFNTBPGGT1B | |
| SCHEMBL7168685 | 0.72 | FNTA (0.47) | HTR1AHTR1DHTR1BFNTAFNTB | |
| SCHEMBL7163140 | 0.71 | FNTA (0.46) | HTR1AHTR1DHTR1BFNTAFNTB | |
| SCHEMBL6409378 | 0.70 | HTR1A (0.35) | HTR1AHTR1DHTR1BFNTAFNTB | |
| SCHEMBL6523879 | 0.69 | FNTA (0.62) | FNTAFNTBPGGT1B | |
| SCHEMBL7168181 | 0.69 | FNTA (0.41) | GPR52FNTAFNTBPGGT1BDNAJA1 | |
| SCHEMBL7247564 | 0.69 | P2RX7 (0.36) | KCNH2HTR1AHTR1DHTR1BFNTA | |
| SCHEMBL6412396 | 0.69 | SIRT2 (0.33) | KCNH2HTR1AHTR1DHTR1BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000025789-A1 | A METHOD OF TREATING ENDOMETRIOSIS | MERCK & CO., INC. (US) | 2000-05-11 | — | — | WO | disclosed |