Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.65 |
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | CASP3 | P42574 | 2/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.54 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8013313 | 0.90 | POLB (0.59) | KMT2AMEN1THRBMAPTPFKFB3 | |
| SCHEMBL8018877 | 0.87 | POLB (0.62) | KMT2AMEN1THRBMAPTPFKFB3 | |
| SCHEMBL1687192 | 0.85 | POLB (0.59) | KMT2AMEN1PKMMAPTPFKFB3 | |
| SCHEMBL8009400 | 0.81 | KMT2A (0.61) | KMT2AMEN1THRBPKMMAPT | |
| SCHEMBL28687053 | 0.80 | MAPT (0.64) | KMT2AMEN1THRBPKMMAPT | |
| SCHEMBL29894244 | 0.80 | MAPT (0.64) | KMT2AMEN1THRBPKMMAPT | |
| SCHEMBL8010205 | 0.79 | MEN1 (0.59) | KMT2AMEN1MAPTTP53SMN1; SMN2 | |
| SCHEMBL3502755 | 0.79 | MEN1 (1.00) | KMT2AMEN1THRBPKMMAPT | |
| SCHEMBL3789938 | 0.79 | KCNK3 (0.71) | KMT2AMEN1MAPTTP53 | |
| SCHEMBL2824710 | 0.78 | THRB (0.81) | KMT2AMEN1THRBPKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000035904-A1 | INHIBITORS OF β-LACTAMASES AND USES THEREFOR | NORTHWESTERN UNIVERSITY (US) | 2000-06-22 | — | — | WO | disclosed |