Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.59 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.54 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28409827 | 0.82 | KCNK3 (0.78) | MEN1KMT2AHPSEKCNK3KCNK9 | |
| SCHEMBL15277111 | 0.82 | MEN1 (0.63) | MEN1KMT2AALDH1A1KCNK3KCNK9 | |
| SCHEMBL18614198 | 0.81 | CA1 (0.53) | MEN1KMT2ACA1CA2ALDH1A1 | |
| SCHEMBL8010202 | 0.81 | FFAR1 (0.67) | MEN1KMT2AHPSEALDH1A1NPC1 | |
| SCHEMBL19857281 | 0.80 | ALDH1A1 (0.66) | MEN1KMT2ACA1CA2ALDH1A1 | |
| SCHEMBL8009397 | 0.79 | KMT2A (0.65) | MEN1KMT2ATP53MAPTSMN1; SMN2 | |
| SCHEMBL9249052 | 0.77 | HPSE (0.84) | MEN1KMT2AHPSEKCNK3KCNK9 | |
| SCHEMBL14372490 | 0.77 | KCNK3 (0.69) | MEN1KMT2ACA1CA2KCNK3 | |
| SCHEMBL1036779 | 0.76 | PKM (0.57) | ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1729812 | 0.76 | CA1 (0.51) | MEN1KMT2ACA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000035904-A1 | INHIBITORS OF β-LACTAMASES AND USES THEREFOR | NORTHWESTERN UNIVERSITY (US) | 2000-06-22 | — | — | WO | disclosed |