Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ITGA1 | P56199 | 2/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8013313 | 0.97 | POLB (0.59) | POLBPFKFB3CA12CA9CA1 | |
| SCHEMBL1687192 | 0.97 | POLB (0.59) | POLBPFKFB3CA12CA9CA1 | |
| SCHEMBL8009397 | 0.87 | KMT2A (0.65) | PFKFB3KMT2AMEN1MAPTTHRB | |
| SCHEMBL15649873 | 0.84 | HSD17B2 (0.56) | POLBCA1CA2KMT2AMEN1 | |
| SCHEMBL7997931 | 0.83 | HTR6 (0.68) | POLBCA9CA1CA2KMT2A | |
| SCHEMBL28632297 | 0.83 | L3MBTL1 (0.58) | CA1CA2KMT2AMEN1MAPT | |
| SCHEMBL12260987 | 0.83 | CA12 (0.59) | CA12CA9CA1CA2KMT2A | |
| SCHEMBL3715141 | 0.80 | CA12 (0.75) | POLBCA12CA9CA1CA2 | |
| SCHEMBL22653513 | 0.80 | POLB (0.65) | POLBPFKFB3CA12CA9CA1 | |
| SCHEMBL664321 | 0.80 | KMT2A (0.75) | POLBCA12CA9CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000035904-A1 | INHIBITORS OF β-LACTAMASES AND USES THEREFOR | NORTHWESTERN UNIVERSITY (US) | 2000-06-22 | — | — | WO | disclosed |