Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL905440 | 1.00 | ALDH1A1 (0.40) | ALDH1A1MAPTLMNAPOLBHSD17B10 | |
| SCHEMBL4416129 | 1.00 | ALDH1A1 (0.40) | ALDH1A1MAPTLMNAPOLBHSD17B10 | |
| SCHEMBL10869191 | 0.90 | TP53 (0.43) | ALDH1A1MAPTLMNAPOLBHSD17B10 | |
| SCHEMBL7507908 | 0.87 | CA2 (0.42) | ALDH1A1MAPTLMNAHSD17B10NPSR1 | |
| SCHEMBL905459 | 0.87 | CA2 (0.42) | ALDH1A1MAPTLMNAHSD17B10NPSR1 | |
| SCHEMBL28046958 | 0.85 | CA1 (0.44) | MAPTTP53CPB2 | |
| SCHEMBL8007457 | 0.85 | ALDH1A1 (0.35) | ALDH1A1MAPTLMNAPOLBHSD17B10 | |
| SCHEMBL19105414 | 0.84 | HDAC1 (0.37) | ALDH1A1MAPTLMNAHSD17B10NPSR1 | |
| SCHEMBL7510756 | 0.84 | ZDHHC7 (0.46) | MAPTTP53CPB2 | |
| SCHEMBL7510923 | 0.84 | ZDHHC7 (0.46) | MAPTTP53CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000024358-A2 | SYNTHESIS AND USES OF THIOPENTONE ENANTIOMERS | THE UNIVERSITY OF SYDNEY (AU) | 2000-05-04 | — | — | WO | disclosed |