SCHEMBL7510756

SCHEMBL7510756

CCCCCCCCCCC(C)C(C(=O)OCC)C(=O)OCC

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ZDHHC7 Q9NXF8 1/20 0.46
FAAH O00519 1/20 0.44
SMPD1 P17405 3/20 0.43
ACE2 Q9BYF1 1/20 0.43
GPR84 Q9NQS5 3/20 0.42
CA1 P00915 2/20 0.42
FFAR1 O14842 1/20 0.42
MAPT P10636 2/20 0.41
TP53 P04637 1/20 0.41
LCK P06239 1/20 0.41
PPARD Q03181 1/20 0.41
ZDHHC20 Q5W0Z9 1/20 0.41
ZDHHC2 Q9UIJ5 1/20 0.41
CPB2 Q96IY4 1/20 0.41
OPRM1 P35372 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18297029 1.00 ZDHHC7 (0.46) ZDHHC7FAAHSMPD1ACE2GPR84
SCHEMBL7510923 1.00 ZDHHC7 (0.46) ZDHHC7FAAHSMPD1ACE2GPR84
SCHEMBL28046958 0.98 CA1 (0.44) ZDHHC7FAAHSMPD1ACE2GPR84
SCHEMBL7507908 0.92 CA2 (0.42) ZDHHC7CA1MAPTTP53CPB2
SCHEMBL905459 0.92 CA2 (0.42) ZDHHC7CA1MAPTTP53CPB2
Malonic Acid SCHEMBL8372739 0.92 ZDHHC7 (0.44) ZDHHC7FAAHACE2GPR84FFAR1
SCHEMBL9331429 0.90 FAAH (0.53) FAAHFFAR1MAPTTP53PPARD
SCHEMBL17287358 0.86 ACE2 (0.46) ZDHHC7FAAHSMPD1ACE2GPR84
SCHEMBL4416129 0.84 ALDH1A1 (0.40) MAPTTP53CPB2
SCHEMBL8009470 0.84 ALDH1A1 (0.40) MAPTTP53CPB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4015511-A1 OXIDATION CATALYSTS BASED ON MACROCYCLIC COMPOUNDS CARNEGIE MELLON UNIVERSITY (US) 2022-06-22 EP disclosed
EP-3353157-B1 OXIDATION CATALYSTS BASED ON MACROCYCLIC COMPOUNDS UNIV CARNEGIE MELLON (US) 2021-11-24 EP disclosed
EP-0914206-B1 LONG-LIVED HOMOGENOUS OXIDATION CATALYSTS UNIV CARNEGIE MELLON (US) 2002-12-11 EP disclosed