Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8009395 | 0.85 | CYP46A1 (0.39) | ALDH1A1CYP46A1PDK2CA12CA1 | |
| SCHEMBL1495535 | 0.85 | KDM1A (0.38) | TDP1LMNAALDH1A1CYP46A1MAPK1 | |
| SCHEMBL1495464 | 0.84 | TDP1 (0.41) | TDP1ALDH1A1CA12CA1CA2 | |
| SCHEMBL7997686 | 0.81 | KDM4E (0.46) | TDP1LMNACYP1A2CYP3A4MAOA | |
| SCHEMBL8008656 | 0.76 | TDP1 (0.48) | TDP1LMNAALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL8008718 | 0.76 | KDM4E (0.46) | MAPK1KDM4ERAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7997679 | 0.75 | WDR5 (0.43) | ALDH1A1 | |
| SCHEMBL8008715 | 0.72 | TDP1 (0.49) | TDP1LMNACYP3A4ALDH1A1CYP46A1 | |
| SCHEMBL8012010 | 0.71 | KDM4E (0.49) | TDP1ALDH1A1MAPK1KDM4ERAB9A | |
| SCHEMBL1495531 | 0.70 | RAB9A (0.51) | ALDH1A1MAPK1KDM4ERAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110985-A2 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2009-09-11 | — | — | WO | disclosed |