Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
| ▸ | PGK2 | P07205 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5672479 | 0.70 | FDPS (0.36) | FDPSALDH1A1GAAPKM | |
| Hydrochloric Acid SCHEMBL5671113 | 0.65 | GGPS1 (0.40) | FDPSCA12CA9CA14 | |
| Hydrochloric Acid SCHEMBL8009766 | 0.62 | PTPN1 (0.34) | PTPN1FDPSALDH1A1TSHRPTPN5 | |
| SCHEMBL4195335 | 0.61 | HDAC8 (0.46) | TSHRMEN1KMT2A | |
| SCHEMBL10040014 | 0.61 | PTPN1 (0.54) | PTPN1FDPSALDH1A1TSHRPTPN5 | |
| SCHEMBL7158867 | 0.60 | PTPN1 (0.58) | PTPN1FDPSALDH1A1TSHRPTPN5 | |
| SCHEMBL1099732 | 0.60 | PTPN1 (0.58) | PTPN1FDPSALDH1A1TSHRPTPN5 | |
| SCHEMBL875768 | 0.60 | PTPN1 (0.58) | PTPN1FDPSALDH1A1TSHRPTPN5 | |
| SCHEMBL7232658 | 0.58 | PTPN1 (0.56) | PTPN1FDPSALDH1A1TSHRPTPN5 | |
| Phosphoric Acid SCHEMBL28453725 | 0.58 | FDPS (0.38) | FDPSCA2CA4CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107561-A | A PHOTOVOLTAIC CELL COMPRISING REDOX SYSTEMS FOR PRODUCTION OF HYDROGEN PEROXIDE FROM OXYGEN AND HYDROGEN GASES, THE PRODUCTION OF HYDROGEN GAS FROM WATER, AND THE REDUCTION OF KETONES TO FORM ALCOHOLS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2000-08-22 | — | — | US | disclosed |
| US-5906892-A | GROUP VIII METAL COMPLEX ON SUPPORT | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1999-05-25 | — | — | US | disclosed |
| US-5695890-A | PHOTOELECTRODE COMPRISING CHARGE TRANSFER COMPLEX; REDOX CATALYSTS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1997-12-09 | — | — | US | disclosed |
| US-5500297-A | PHOTOINDUCED CHARGE SEPARATION, ORGANIC PILLARS, REPEATING CATIONIC CENTERS AND METAL PHOSPHONATES WITH ENTRAPPED COLLOIDAL PARTICLES OF PALLADIUM OR PLATINUM | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1996-03-19 | — | — | US | disclosed |