Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 5/20 | 0.40 |
| ▸ | FDPS | P14324 | 6/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 3/20 | 0.33 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | ACP3 | P15309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12060616 | 0.76 | GGPS1 (0.39) | GGPS1FDPSCA12MMP2CA9 | |
| Hydrochloric Acid SCHEMBL5672483 | 0.70 | FDPS (0.46) | GGPS1FDPS | |
| SCHEMBL12257829 | 0.68 | GGPS1 (0.54) | GGPS1FDPS | |
| SCHEMBL14199555 | 0.68 | GGPS1 (0.37) | GGPS1FDPSSRC | |
| Hydrochloric Acid SCHEMBL7005196 | 0.67 | KDM4E (0.49) | — | |
| SCHEMBL15153589 | 0.65 | SMN1; SMN2 (0.34) | — | |
| Iodide SCHEMBL8962414 | 0.65 | KDM4E (0.44) | — | |
| Hydrochloric Acid SCHEMBL8009761 | 0.65 | PTPN1 (0.35) | FDPSCA12CA9CA14 | |
| SCHEMBL12060607 | 0.65 | GGPS1 (0.51) | GGPS1FDPSLAP3ANPEPACP3 | |
| Bromide SCHEMBL11215457 | 0.64 | ALDH1A1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1004143-A4 | CHARGE GENERATORS IN HETEROLAMELLAR MULTILAYER THIN FILMS | UNIV SOUTHERN CALIFORNIA (US) | 2006-04-12 | — | — | EP | disclosed |
| EP-1394185-A1 | Derivative of polyvinylpyridine | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2004-03-03 | — | — | EP | disclosed |
| EP-1004143-A1 | CHARGE GENERATORS IN HETEROLAMELLAR MULTILAYER THIN FILMS | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2000-05-31 | — | — | EP | disclosed |
| EP-0871985-A4 | HETEROLAMELLAR PHOTOVOLTAIC FILMS | UNIV PRINCETON (US) | 1999-06-09 | — | — | EP | disclosed |
| WO-1999003154-A1 | CHARGE GENERATORS IN HETEROLAMELLAR MULTILAYER THIN FILMS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 1999-01-21 | — | — | WO | disclosed |
| EP-0871985-A1 | HETEROLAMELLAR PHOTOVOLTAIC FILMS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997024775-A1 | HETEROLAMELLAR PHOTOVOLTAIC FILMS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1997-07-10 | — | — | WO | disclosed |