Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TYMP | P19971 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8021664 | 0.82 | LMNA (0.52) | LMNATSHRKMT2ATYMPALDH1A1 | |
| SCHEMBL8021661 | 0.82 | LMNA (0.52) | LMNATSHRKMT2ATYMPALDH1A1 | |
| SCHEMBL2454848 | 0.79 | TSHR (0.52) | LMNATSHRKMT2ACA2CA12 | |
| SCHEMBL2454844 | 0.79 | TSHR (0.52) | LMNATSHRKMT2ACA2CA12 | |
| SCHEMBL14278404 | 0.79 | TSHR (0.52) | LMNATSHRKMT2ACA2CA12 | |
| SCHEMBL22830171 | 0.76 | KIF11 (0.35) | LMNATSHRKMT2ATYMPCA2 | |
| SCHEMBL9393500 | 0.75 | TSHR (0.50) | LMNATSHRKMT2AALDH1A1CYP2D6 | |
| SCHEMBL18343982 | 0.75 | TSHR (0.50) | LMNATSHRKMT2AALDH1A1CYP2D6 | |
| SCHEMBL20095195 | 0.74 | TSHR (0.59) | LMNATSHRKMT2ACA2CA12 | |
| SCHEMBL23778463 | 0.74 | TSHR (0.44) | LMNATSHRKMT2ATYMPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711766-B1 | 7-FLUORO-2, 3-DIDEHYDROSIALIC ACID AND INTERMEDIATE FOR SYNTHESIS THEREOF | DAIKIN IND LTD (JP) | 2000-02-16 | — | — | EP | claimed |
| US-5627290-A | 2,3-didehydrosialic acid substituted with fluorine at 7-position and synthetic intermediate thereof | DAIKIN INDUSTRIES, LTD. (JP) | 1997-05-06 | — | — | US | claimed |
| EP-0711766-A1 | 7-FLUORO-2, 3-DIDEHYDROSIALIC ACID AND INTERMEDIATE FOR SYNTHESIS THEREOF | DAIKIN INDUSTRIES, LIMITED (JP) | 1996-05-15 | — | — | EP | claimed |
| EP-0711766-B1 | 7-FLUORO-2, 3-DIDEHYDROSIALIC ACID AND INTERMEDIATE FOR SYNTHESIS THEREOF | DAIKIN IND LTD (JP) | 2000-02-16 | — | — | EP | disclosed |
| US-5627290-A | 2,3-didehydrosialic acid substituted with fluorine at 7-position and synthetic intermediate thereof | DAIKIN INDUSTRIES, LTD. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0711766-A1 | 7-FLUORO-2, 3-DIDEHYDROSIALIC ACID AND INTERMEDIATE FOR SYNTHESIS THEREOF | DAIKIN INDUSTRIES, LIMITED (JP) | 1996-05-15 | — | — | EP | disclosed |