Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.72 |
| ▸ | ABL1 | P00519 | 1/20 | 0.72 |
| ▸ | ABL2 | P42684 | 1/20 | 0.72 |
| ▸ | VCP | P55072 | 5/20 | 0.60 |
| ▸ | GALR2 | O43603 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | SYK | P43405 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | FBP1 | P09467 | 15/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2052285 | 0.84 | EGFR (1.00) | EGFRABL1ABL2VCPGALR2 | |
| SCHEMBL2052283 | 0.84 | EGFR (1.00) | EGFRABL1ABL2VCPGALR2 | |
| SCHEMBL29371330 | 0.84 | EGFR (1.00) | EGFRABL1ABL2VCPGALR2 | |
| SCHEMBL3667079 | 0.81 | EGFR (0.93) | EGFRABL1ABL2VCPGALR2 | |
| SCHEMBL3667077 | 0.81 | EGFR (0.93) | EGFRABL1ABL2VCPGALR2 | |
| SCHEMBL8015814 | 0.80 | FBP1 (0.53) | EGFRABL1ABL2VCPGALR2 | |
| SCHEMBL793577 | 0.79 | FBP1 (0.58) | EGFRABL1ABL2VCPGALR2 | |
| SCHEMBL8012584 | 0.79 | EGFR (0.72) | EGFRABL1ABL2VCPGALR2 | |
| SCHEMBL2027152 | 0.79 | EGFR (0.72) | EGFRABL1ABL2VCPGALR2 | |
| SCHEMBL13773077 | 0.79 | EGFR (0.72) | EGFRABL1ABL2VCPGALR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162614-A | Sugar ester derivatives, reagents for measurement of hydrolase activity and methods for measurement of hydrolase activity | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2000-12-19 | — | — | US | disclosed |
| EP-0346912-B1 | Sugar ester derivatives, reagents for measurement of hydrolase activity and methods for measurement of hydrolase activity | TOYO BOSEKI (JP) | 1997-12-17 | — | — | EP | disclosed |
| EP-0346912-A2 | Sugar ester derivatives, reagents for measurement of hydrolase activity and methods for measurement of hydrolase activity | Toyo Boseki Kabushiki Kaisha (JP) | 1989-12-20 | — | — | EP | disclosed |