Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MITF | O75030 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-Phenylbenzamide SCHEMBL28741338 | 0.91 | SIRT1 (0.69) | PTPN1HDAC2HDAC8HDAC6MEN1 | |
| SCHEMBL3659389 | 0.91 | FFAR1 (0.79) | FFAR1PTPN1HDAC2HDAC8HDAC6 | |
| SCHEMBL3659600 | 0.85 | FFAR1 (0.89) | FFAR1PTPN1HDAC2HDAC8HDAC6 | |
| SCHEMBL1315526 | 0.84 | PTPN1 (0.87) | FFAR1PTPN1HDAC2HDAC8HDAC6 | |
| SCHEMBL19857281 | 0.84 | ALDH1A1 (0.66) | PTPN1HDAC2HDAC8HDAC6ALDH1A1 | |
| Terephthalic Acid SCHEMBL28872662 | 0.84 | PTPN1 (0.85) | FFAR1PTPN1HDAC2HDAC8HDAC6 | |
| SCHEMBL19501650 | 0.84 | SIRT1 (0.82) | FFAR1PTPN1HDAC2HDAC8HDAC6 | |
| SCHEMBL14715847 | 0.82 | PTPN1 (0.84) | FFAR1PTPN1HDAC2HDAC8HDAC6 | |
| SCHEMBL28419632 | 0.82 | MITF (0.81) | FFAR1PTPN1HDAC2HDAC8HDAC6 | |
| SCHEMBL900903 | 0.82 | MITF (0.81) | FFAR1PTPN1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000035904-A1 | INHIBITORS OF β-LACTAMASES AND USES THEREFOR | NORTHWESTERN UNIVERSITY (US) | 2000-06-22 | — | — | WO | disclosed |