Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.59 |
| ▸ | KDM1A | O60341 | 5/20 | 0.56 |
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | RCOR1 | Q9UKL0 | 4/20 | 0.55 |
| ▸ | TGM2 | P21980 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985522 | 0.84 | KDM1A (0.59) | HRH3KDM1AMAOAMAOBRCOR1 | |
| SCHEMBL2635334 | 0.83 | KDM1A (0.65) | HRH3KDM1AMAOAMAOBRCOR1 | |
| SCHEMBL2635331 | 0.83 | KDM1A (0.65) | HRH3KDM1AMAOAMAOBRCOR1 | |
| SCHEMBL2635332 | 0.83 | KDM1A (0.65) | HRH3KDM1AMAOAMAOBRCOR1 | |
| SCHEMBL20530488 | 0.77 | SMN1; SMN2 (0.53) | — | |
| SCHEMBL30251765 | 0.77 | SMN1; SMN2 (0.58) | — | |
| SCHEMBL14824682 | 0.76 | NAMPT (0.65) | HRH3KDM1AMAOAMAOBRCOR1 | |
| SCHEMBL28697724 | 0.75 | KDM1A (0.62) | HRH3KDM1AMAOAMAOBRCOR1 | |
| SCHEMBL2635348 | 0.74 | HRH3 (1.00) | HRH3KDM1AMAOAMAOBRCOR1 | |
| SCHEMBL2635167 | 0.74 | HRH3 (1.00) | HRH3KDM1AMAOAMAOBRCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043266-A | MICROBIOCIDES TREATING GRAM-POSITIVE BACTERIA INFECTIONS AND PERSONS WITH AIDS | PHARMACIA & UPJOHN COMPANY (US) | 2000-03-28 | — | — | US | disclosed |