Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7018637 | 0.92 | AGTR2 (0.45) | — | |
| SCHEMBL8359329 | 0.86 | AGTR2 (0.46) | — | |
| SCHEMBL7022032 | 0.85 | AGTR2 (0.46) | — | |
| SCHEMBL7016132 | 0.84 | — | — | |
| SCHEMBL7016995 | 0.82 | AGTR2 (0.45) | — | |
| SCHEMBL8010343 | 0.79 | PPARG (0.43) | — | |
| SCHEMBL7011145 | 0.78 | PPARG (0.51) | — | |
| SCHEMBL5138326 | 0.78 | AGTR1 (0.61) | — | |
| SCHEMBL7017665 | 0.78 | — | — | |
| SCHEMBL7019646 | 0.78 | AGTR2 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100252-A | SPECIFIED COMPOUNDS INCLUDING METHYL 2-BUTYL-1-((2'-(2-OXO-3H-1,2,3,5-OXATHIADIAZOL-4-YL)BIPHENYL) METHYL)-BENZIMIDAZOLE-7-CARBOXYLATE; USE TO TREAT CIRCULATORY DISEASES SUCH AS HYPERTENSIVE DISEASES AND HEART DISEASES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-08-08 | — | — | US | disclosed |