Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7018644 | 0.91 | PPARG (0.48) | PPARG | |
| SCHEMBL7016139 | 0.84 | PPARG (0.52) | PPARG | |
| SCHEMBL7011145 | 0.83 | PPARG (0.51) | PPARG | |
| SCHEMBL7019531 | 0.81 | PPARG (0.60) | PPARG | |
| SCHEMBL7017003 | 0.81 | AGTR2 (0.43) | — | |
| SCHEMBL8359329 | 0.79 | AGTR2 (0.46) | PPARG | |
| SCHEMBL8010338 | 0.79 | MEN1 (0.40) | — | |
| SCHEMBL5138326 | 0.78 | AGTR1 (0.61) | PPARG | |
| SCHEMBL7019109 | 0.77 | AGTR2 (0.64) | PPARG | |
| SCHEMBL7103160 | 0.76 | PPARG (0.50) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100252-A | SPECIFIED COMPOUNDS INCLUDING METHYL 2-BUTYL-1-((2'-(2-OXO-3H-1,2,3,5-OXATHIADIAZOL-4-YL)BIPHENYL) METHYL)-BENZIMIDAZOLE-7-CARBOXYLATE; USE TO TREAT CIRCULATORY DISEASES SUCH AS HYPERTENSIVE DISEASES AND HEART DISEASES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-08-08 | — | — | US | disclosed |