Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | YWHAG | P61981 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
| ▸ | QDPR | P09417 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17320655 | 0.82 | ALOX5 (0.55) | ALOX5PTPN1YWHAGMEN1KMT2A | |
| SCHEMBL3695981 | 0.77 | ESR1 (0.43) | ALOX5PTPN1YWHAGRAB9APPARG | |
| SCHEMBL3691459 | 0.77 | MEN1 (0.40) | ALOX5PTPN1YWHAGRAB9AMEN1 | |
| SCHEMBL3695721 | 0.77 | HSD17B10 (0.43) | ALOX5PTPN1YWHAGCYP3A4 | |
| SCHEMBL242386 | 0.77 | DRD3 (0.47) | ALOX5PTPN1YWHAGRAB9AMEN1 | |
| SCHEMBL1587499 | 0.77 | ALOX15 (0.43) | ALOX5PTPN1YWHAGRAB9AMEN1 | |
| SCHEMBL26427919 | 0.73 | ACMSD (0.58) | ALOX5PTPN1MEN1KMT2AHTT | |
| SCHEMBL3690573 | 0.73 | PPARG (0.64) | ALOX5PTPN1MEN1KMT2APPARG | |
| SCHEMBL9423755 | 0.73 | APP (0.40) | ALOX5PTPN1YWHAGRAB9AMEN1 | |
| SCHEMBL9451016 | 0.71 | MEN1 (0.44) | RAB9AMEN1KMT2ACCNB2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009098287-A1 | PHENYL-PRENYL DERIVATIVES, OF MARINE AND SYNTHETIC ORIGIN, FOR THE TREATMENT OF COGNITIVE, NEURODEGENERATIVE OR NEURONAL DISEASES OR DISORDERS | NOSCIRA S.A. (ES) | 2009-08-13 | — | — | WO | disclosed |