Aniline

Aniline

SCHEMBL8010657

Nc1c(-c2ccccc2)ccc2ccccc12.Nc1ccccc1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCZ Q05513 1/20 0.43
TSHR P16473 3/20 0.42
MAPT P10636 3/20 0.42
HSD17B10 Q99714 6/20 0.41
TDP1 Q9NUW8 3/20 0.41
CYP3A4 P08684 2/20 0.41
TAAR1 Q96RJ0 1/20 0.41
ALDH1A1 P00352 6/20 0.41
CYP2A6 P11509 1/20 0.41
CDK4 P11802 1/20 0.40
CCND1 P24385 1/20 0.40
HPGD P15428 4/20 0.39
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
KDM4E B2RXH2 3/20 0.39
MPI P34949 1/20 0.39
KEAP1 Q14145 1/20 0.39
GLA P06280 2/20 0.39
ATM Q13315 2/20 0.39
POLB P06746 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21068 0.94 ALDH1A1 (0.46) TSHRMAPTHSD17B10TDP1CYP3A4
SCHEMBL29423352 0.94 ALDH1A1 (0.46) TSHRMAPTHSD17B10TDP1CYP3A4
SCHEMBL30574434 0.94 ALDH1A1 (0.46) TSHRMAPTHSD17B10TDP1CYP3A4
SCHEMBL15271981 0.90 HSD17B10 (0.43) PRKCZTSHRMAPTHSD17B10TDP1
SCHEMBL29798181 0.90 HSD17B10 (0.43) PRKCZTSHRMAPTHSD17B10TDP1
SCHEMBL23443653 0.90 PRKCZ (0.53) PRKCZTSHRMAPTHSD17B10TDP1
SCHEMBL23443652 0.85 MAOA (0.48) TSHRMAPTHSD17B10TDP1CYP3A4
SCHEMBL19857293 0.85 HPRT1 (0.54) TSHRMAPTHSD17B10TDP1CYP3A4
SCHEMBL6062322 0.81 ALDH1A1 (0.55) TSHRMAPTHSD17B10TDP1CYP3A4
SCHEMBL29705759 0.81 ALDH1A1 (0.55) TSHRMAPTHSD17B10TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0972194-A2 COMPOSITIONS AND METHODS FOR INHIBITING LIGHT-INDUCED INACTIVATION OF BIOLOGICAL REAGENTS BIOSITE DIAGNOSTICS INC. (US) 2000-01-19 EP disclosed
WO-1998045705-A2 COMPOSITIONS AND METHODS FOR INHIBITING LIGHT-INDUCED INACTIVATION OF BIOLOGICAL REAGENTS BIOSITE DIAGNOSTICS INCORPORATED (US) 1998-10-15 WO disclosed