Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 10/20 | 0.39 |
| ▸ | CYP51A1 | Q16850 | 7/20 | 0.39 |
| ▸ | PYGM | P11217 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8006223 | 0.88 | PYGL (0.39) | PYGLCYP51A1PYGMSMYD3MEN1 | |
| SCHEMBL4048476 | 0.86 | PYGL (0.41) | PYGLCYP51A1PYGMSMYD3MEN1 | |
| SCHEMBL7996360 | 0.82 | SMYD3 (0.36) | PYGLCYP51A1PYGMSMYD3MEN1 | |
| SCHEMBL8004929 | 0.81 | SMYD3 (0.37) | PYGLCYP51A1PYGMSMYD3MEN1 | |
| SCHEMBL7997127 | 0.80 | STAT6 (0.36) | PYGLCYP51A1PYGMSMYD3 | |
| SCHEMBL8004923 | 0.79 | PYGL (0.37) | PYGLCYP51A1SMYD3 | |
| SCHEMBL8004714 | 0.78 | ALOX15 (0.40) | PYGLCYP51A1PYGMSMYD3 | |
| SCHEMBL7996364 | 0.76 | ALB (0.36) | CYP51A1 | |
| SCHEMBL7986132 | 0.74 | SMYD3 (0.47) | PYGLCYP51A1PYGMSMYD3MEN1 | |
| SCHEMBL8002427 | 0.74 | SMYD3 (0.47) | PYGLCYP51A1PYGMSMYD3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009111680-A1 | TRPV4 ANTAGONISTS | SMITHLINE BEECHAM CORPORATION (US) | 2009-09-11 | — | — | WO | disclosed |